Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

BACKGROUND: Anti-TNF drugs are effective treatments for the management of Crohn's disease but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors that predict primary non-response at week 14 after starting treatment, non-remission at week 54, and adverse event...

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Bibliographic Details
Main Authors: Kennedy, NA, Heap, GA, Green, HD, Hamilton, B, Bewshea, C, Walker, GJ, Thomas, A, Nice, R, Perry, MH, Bouri, S, Chanchlani, N, Heerasing, NM, Hendy, P, Lin, S, Gaya, DR, Cummings, JRF, Selinger, CP, Lees, CW, Hart, AL, Parkes, M, Sebastian, S, Mansfield, JC, Irving, PM, Lindsay, J, Russell, RK
Other Authors: Simmons, A
Format: Journal article
Language:English
Published: Elsevier 2019

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