Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain
Objective: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system associated with pathogenic autoantibodies against the astrocyte water channel protein aquaporin-4 (AQP4). The presence of neutrophils is a characteristic feature in NMO lesions in humans. Neu...
Hoofdauteurs: | Saadoun, S, Waters, P, MacDonald, C, Bell, B, Vincent, A, Verkman, A, Papadopoulos, M |
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Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2012
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