Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain
Objective: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system associated with pathogenic autoantibodies against the astrocyte water channel protein aquaporin-4 (AQP4). The presence of neutrophils is a characteristic feature in NMO lesions in humans. Neu...
主要な著者: | , , , , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2012
|