The costs of close contacts: visualizing the energy landscape of cell contacts at the nanoscale

Cell-cell contacts often underpin signaling between cells. For immunology, the binding of a T cell receptor to an antigen-presenting pMHC initiates downstream signaling and an immune response. Although this contact is mediated by proteins on both cells creating interfaces with gap sizes typically ar...

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Bibliographic Details
Main Authors: Kulenkampff, K, Lippert, AH, McColl, J, Santos, AF, Ponjavic, A, Jenkins, E, Humphrey, J, Winkel, A, Franze, K, Lee, SF, Davis, SJ, Klenerman, D
Format: Journal article
Language:English
Published: Elsevier 2020