The costs of close contacts: visualizing the energy landscape of cell contacts at the nanoscale
Cell-cell contacts often underpin signaling between cells. For immunology, the binding of a T cell receptor to an antigen-presenting pMHC initiates downstream signaling and an immune response. Although this contact is mediated by proteins on both cells creating interfaces with gap sizes typically ar...
Huvudupphovsmän: | Kulenkampff, K, Lippert, AH, McColl, J, Santos, AF, Ponjavic, A, Jenkins, E, Humphrey, J, Winkel, A, Franze, K, Lee, SF, Davis, SJ, Klenerman, D |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
Elsevier
2020
|
Liknande verk
Liknande verk
-
Single-molecule light-sheet imaging of suspended T cells
av: Ponjavic, A, et al.
Publicerad: (2018) -
Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling
av: Chen, KY, et al.
Publicerad: (2021) -
Initiation of T cell signaling by CD45 segregation at 'close contacts'
av: Chang, VT, et al.
Publicerad: (2016) -
Nanoscale T-cell membrane protein imaging across complex topography using accelerated large depth-of-field localisation microscopy
av: Ponjavic Aleks, et al.
Publicerad: (2024-01-01) -
Antigen discrimination by T cells relies on size-constrained microvillar contact
av: Edward Jenkins, et al.
Publicerad: (2023-03-01)