Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation.
A key issue in stem cell biology is the differentiation of homogeneous stem cells towards different fates which are also organized into desired configurations. Little is known about the mechanisms underlying the process of periodic patterning. Feather explants offer a fundamental and testable model...
Hoofdauteurs: | Lin, C, Jiang, T, Baker, R, Maini, P, Widelitz, R, Chuong, C |
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Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2009
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