XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.

XRCC1 is a scaffold protein that interacts with several DNA repair proteins and plays a critical role in DNA base excision repair (BER). XRCC1 protein is in a tight complex with DNA ligase IIIalpha (Lig III) and this complex is involved in the ligation step of both BER and repair of DNA single stran...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Parsons, J, Dianova, I, Finch, D, Tait, P, Ström, C, Helleday, T, Dianov, G
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2010

Eitemau Tebyg

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
gan: Ström, C, et al.
Cyhoeddwyd: (2011)

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
gan: Dianova, I, et al.
Cyhoeddwyd: (2004)

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
gan: Parsons, J, et al.
Cyhoeddwyd: (2005)

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
gan: Parsons, J, et al.
Cyhoeddwyd: (2008)

Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.
gan: Meisenberg, C, et al.
Cyhoeddwyd: (2012)

USP7/HAUSP stimulates repair of oxidative DNA lesions.
gan: Khoronenkova, S, et al.
Cyhoeddwyd: (2011)

APE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanine.
gan: Parsons, J, et al.
Cyhoeddwyd: (2005)

Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair
gan: Savolainen, L, et al.
Cyhoeddwyd: (2009)

Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks.
gan: Woodhouse, B, et al.
Cyhoeddwyd: (2008)

Repair of abasic sites in DNA.
gan: Dianov, G, et al.
Cyhoeddwyd: (2003)

Polymorphisms of the DNA repair genes XRCC1 and XRCC3 in a Brazilian population
gan: Márcia Cristina Duarte, et al.
Cyhoeddwyd: (2005-09-01)

End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair.
gan: Parsons, J, et al.
Cyhoeddwyd: (2005)

Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
gan: Parsons, J, et al.
Cyhoeddwyd: (2005)

Polymorphisms in DNA repair genes XRCC2 and XRCC3 risk of gastric cancer in Turkey
gan: İlhami Gok, et al.
Cyhoeddwyd: (2014-09-01)

Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer
gan: S. S. Rakitin, et al.
Cyhoeddwyd: (2011-12-01)

Polymorphie DNA repair genes XRCC1 and XRCC3 and the risk for cervical cancer in Brazilian patients
gan: Fabricio Colacino-Silva, et al.
Cyhoeddwyd: (2017-01-01)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
gan: Parsons, J, et al.
Cyhoeddwyd: (2009)

DNA-PKcs and PARP1 bind to unresected stalled DNA replication forks where they recruit XRCC1 to mediate repair
gan: Sing, S, et al.
Cyhoeddwyd: (2016)

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.
gan: Markkanen, E, et al.
Cyhoeddwyd: (2012)

DNA Repair Genes and Chronic Myeloid Leukemia: XPD (751), XRCC1 (399), XRCC4-Intron 3, XRCC4 (1394) Gene Polymorphisms
gan: Istemi SERIN, et al.
Cyhoeddwyd: (2021-02-01)

Xrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes
gan: Xuebi Cai, et al.
Cyhoeddwyd: (2023-07-01)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
gan: Parsons, J, et al.
Cyhoeddwyd: (2011)

The importance of XRCC2 in RAD51-related DNA damage repair.
gan: Tambini, C, et al.
Cyhoeddwyd: (2010)

DNA repair gene XRCC1 polymorphisms and bladder cancer risk
gan: Sak, S, et al.
Cyhoeddwyd: (2007)

DNA repair gene <it>XRCC1 </it>polymorphisms and bladder cancer risk
gan: Bishop D Timothy, et al.
Cyhoeddwyd: (2007-04-01)

Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.
gan: Parsons, J, et al.
Cyhoeddwyd: (2012)

Regulation of DNA repair by ubiquitylation.
gan: Dianov, G, et al.
Cyhoeddwyd: (2011)

The Phosphorylation of PDX-1 by Protein Kinase CK2 Is Crucial for Its Stability
gan: Sabrina Klein, et al.
Cyhoeddwyd: (2016-12-01)

Co-ordination of DNA single strand break repair.
gan: Dianov, G, et al.
Cyhoeddwyd: (2007)

Polymorphisms in <it>XPC</it>, <it>XPD</it>, <it>XRCC1</it>, and <it>XRCC3 </it>DNA repair genes and lung cancer risk in a population of Northern Spain
gan: Tardón Adonina, et al.
Cyhoeddwyd: (2007-08-01)

DNA Repair Genes XRCC1, XRCC3, XPD, and OGG1 Polymorphisms among the Central Region Population of Saudi Arabia
gan: Mohammad Alanazi, et al.
Cyhoeddwyd: (2013-01-01)

Co-ordination of base excision repair and genome stability.
gan: Parsons, J, et al.
Cyhoeddwyd: (2013)

Role of RAD51C and XRCC3 in genetic recombination and DNA repair.
gan: Liu, Y, et al.
Cyhoeddwyd: (2007)

CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity
gan: Valeria Catena, et al.
Cyhoeddwyd: (2021-07-01)

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair.
gan: Taylor, R, et al.
Cyhoeddwyd: (2000)

Homologous recombination DNA repair gene RAD51, XRCC2 & XRCC3 polymorphisms and breast cancer risk in South Indian women
gan: Taruna Rajagopal, et al.
Cyhoeddwyd: (2022-01-01)

ARF induction in response to DNA strand breaks is regulated by PARP1
gan: Orlando, G, et al.
Cyhoeddwyd: (2013)

Influence of XRCC1 Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair
gan: Silvia Sterpone, et al.
Cyhoeddwyd: (2010-01-01)

DNA repair gene XRCC7 G6721T variant and susceptibility to colorectal cancer
gan: Mostafa Saadat, et al.
Cyhoeddwyd: (2016-10-01)

T. cruzi DNA polymerase beta (Tcpolβ) is phosphorylated in vitro by CK1, CK2 and TcAUK1 leading to the potentiation of its DNA synthesis activity.
gan: Edio Maldonado, et al.
Cyhoeddwyd: (2021-07-01)