Novel enzymological profiles of human 11beta-hydroxysteroid dehydrogenase type 1.

The human enzyme 11beta-hydroxysteroid dehydrogenase (11beta-HSD) catalyzes the reversible oxidoreduction of 11beta-OH/11-oxo groups of glucocorticoid hormones. Besides this important endocrinological property, the type 1 isozyme (11beta-HSD1) mediates reductive phase I reactions of several carbonyl...

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Bibliographic Details
Main Authors: Hult, M, Nobel, C, Abrahmsen, L, Nicoll-Griffith, D, Jörnvall, H, Oppermann, U
Format: Journal article
Language:English
Published: 2001