The role of adenosine A2A receptor signalling in cardiac fibrosis

<p>Myocardial fibrosis contributes to the pathogenesis of diverse forms of cardiac hypertrophy. Recent evidence suggests a crucial role for purinergic signalling in the formation of tissue fibrosis. In particular, inhibition of adenosine A2A receptors (A2AR) in animal models for hepatic and sk...

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Bibliographic Details
Main Authors: Stockenhuber, A, Ashrafian, H, Watkins, H
Format: Thesis
Published: 2015