Potent anti‐inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells

Background and Purpose To investigate whether a narrow spectrum kinase inhibitor RV1088, which simultaneously targets specific MAPKs, Src and spleen tyrosine kinase (Syk), is more effective at inhibiting inflammatory signalling in rheumatoid arthritis (RA) than single kinase inhibitors (SKIs). Exper...

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Bibliographic Details
Main Authors: To, W, Aungier, S, Cartwright, A, Ito, K, Midwood, K
Format: Journal article
Language:English
Published: Wiley 2015