Functional analysis of polymorphisms associated with osteoarthritis susceptibility that affect cis-regulation
Osteoarthritis (OA) is a common, multifactorial disease that is characterized by focal degeneration of the smooth articular cartilage in any of the synovial joints. Although the underlying molecular mechanisms for OA are still not fully understood, epidemiological studies have evidenced a significan...
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Format: | Thesis |
Language: | English |
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2008
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