Aberrant methylation underlies insulin gene expression in human insulinoma

Human insulinomas are rare, benign, slowly proliferating, insulin-producing beta cell tumors that provide a molecular “recipe” or “roadmap” for pathways that control human beta cell regeneration. An earlier study revealed abnormal methylation in the imprinted p15.5-p15.4 region of chromosome 11, kno...

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Bibliographic Details
Main Authors: Karaoke, E, Wang, H, Inabnet, W, Thakker, RV, Libutti, S, Fernandez-Ranvier, G, Such, H, Stevenson, M, Kinoshita, Y, Donovan, M, Antipin, Y, Li, Y, Liu, X, Jin, F, Wang, P, Uzilov, A, Argmann, C, Schadt, EE, Stewart, AF, Scott, DK, Lambertini, L
Format: Journal article
Language:English
Published: Springer Nature 2020
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