Use of ferrous iron by metallo-β-lactamases.
Metallo--lactamases (MBLs) catalyse the hydrolysis of almost all -lactam antibacterials including the latest generation carbapenems and are a growing worldwide clinical problem. It is proposed that MBLs employ one or two zinc ion cofactors in vivo. Isolated MBLs are reported to use transition meta...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2016
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