Use of ferrous iron by metallo-β-lactamases.

Use of ferrous iron by metallo-β-lactamases.

Metallo--lactamases (MBLs) catalyse the hydrolysis of almost all -lactam antibacterials including the latest generation carbapenems and are a growing worldwide clinical problem. It is proposed that MBLs employ one or two zinc ion cofactors in vivo. Isolated MBLs are reported to use transition meta...

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Bibliografische gegevens
Hoofdauteurs:	Cahill, S, Tarhonskaya, H, Rydzik, A, Flashman, E, McDonough, M, Schofield, C, Brem, J
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	Elsevier 2016

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