Inhibitory effect of calcium on non-heme iron absorption may be related to translocation of DMT-1 at the apical membrane of enterocytes.

Many studies show that calcium reduces iron absorption from single meals, but the underlying mechanism is not known. We tested the hypothesis that calcium alters the expression and/or functionality of iron transport proteins. Differentiated Caco-2 cells were treated with ferric ammonium citrate and...

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Bibliographic Details
Main Authors: Thompson, B, Sharp, P, Elliott, R, Fairweather-Tait, S
Format: Journal article
Language:English
Published: 2010