Studies on deacetoxy/deacetylcephalosporin C synthase

Studies on deacetoxy/deacetylcephalosporin C synthase

<p>This thesis describes an investigation of the mechanism of the bifunctional, a-ketoglutarate dependent dioxygenase, deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS), which catalyses the ring-expansion of penicillin N to deacetoxycephalosporin C (DAOC) and the hydroxylation of this to...

Descripció completa

Dades bibliogràfiques
Autors principals:	Pereira, I, Pereira, Inês Antunes Cardoso
Altres autors:	Baldwin, J
Format:	Thesis
Idioma:	English
Publicat:	1993
Matèries:	Penicillin Enzymes Cephalosporins Ring formation (Chemistry) Synthesis

Ítems similars

The mechanism of the enzymatic ring expansion of penicillin N to deacetoxycephalosporin C
per: Crouch, N, et al.
Publicat: (1988)

STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES
per: Baldwin, J, et al.
Publicat: (1991)

Synthesis of cephalosporins and penicillins by enzymatic acylation /
per: Takeshi Takahashi

Enzymatic synthesis of penicillins and cephalosporins by penicillin acylase /

Conversion of penicillin N to cephalosporin(s) by cell-free extracts of cephalosporium acremonium /
per: 350976 Kohsaka, M., et al.

Oxidation of deacetylcephalosporin C by deacetoxycephalosporin C/deacetylcephalosporin C synthase.
per: Baldwin, J, et al.
Publicat: (1992)

Prolonged versus intermittent β-lactam infusion in sepsis: a systematic review and meta-analysis of randomized controlled trials
per: Yang Zhao, et al.
Publicat: (2024-02-01)

Clinical Pharmacokinetics of Penicillins, Cephalosporins and Aminoglycosides in the Neonate: A Review
per: Gian Maria Pacifici
Publicat: (2010-08-01)

Allergy to cephalosporin antibiotics in children
per: Atanasković-Marković Marina, et al.
Publicat: (2003-01-01)

Management of Beta-Lactam Antibiotics Allergy: A Real-Life Study
per: Sarah Iuliano, et al.
Publicat: (2022-04-01)

Warfarin and Antibiotics: Drug Interactions and Clinical Considerations
per: Alexis J. Vega, et al.
Publicat: (2023-07-01)

Penicillin Allergy and Cross-reactivity with other Beta-lactams.
per: Mohammadreza Javadi, et al.
Publicat: (2015-10-01)

Treatment Challenges of Group A Beta-hemolytic Streptococcal Pharyngo-Tonsillitis
per: Itzhak Brook
Publicat: (2016-06-01)

Intrapartum Group B Streptococcus Antibiotic Prophylaxis in Penicillin Allergic Pregnant Women
per: Nerlyne Desravines, et al.
Publicat: (2019-07-01)

Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase.
per: Lloyd, MD, et al.
Publicat: (2004)

Cephalosporin Induced Toxic Epidermal Necrolysis and Subsequent Penicillin Drug Exanthem
per: Amanda Lam, et al.
Publicat: (2008-01-01)

Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review
per: Abdul Haseeb, et al.
Publicat: (2022-09-01)

Empirical fluoroquinolones versus broad-spectrum beta-lactams for Gram-negative bloodstream infections in the absence of antimicrobial resistance risk factors
per: Majdi N. Al-Hasan, et al.
Publicat: (2020-09-01)

Penicillin Allergy and Perioperative Anaphylaxis
per: Allison Ramsey, et al.
Publicat: (2022-06-01)

Modification of iron binding ligands in isopenicillin n synthase
per: Sami, M, et al.
Publicat: (1998)

Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams
per: Søren Brøgger Christensen
Publicat: (2021-10-01)

Hfq mutation confers increased cephalosporin resistance in Klebsiella pneumoniae
per: Li Xinran, et al.
Publicat: (2017-01-01)

Effect of inoculum size on the antibiotic susceptibilities of β-lactamase positive isolates of Moraxella catarrhalis
per: J. Vraneš, et al.
Publicat: (2005-08-01)

Stabilization of penicillin amidohydrolase immobilized on Eupergit C /
per: 421150 Sauber, K., et al.

Enzymatic biosynthesis of cephalexin /
per: Rhee, D. K.

Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models
per: André Wieringa, et al.
Publicat: (2023-11-01)

Thin Layer Chromatographic Analysis of Beta-Lactam Antibiotics
per: Gabriel Hancu, et al.
Publicat: (2013-08-01)

Transcriptome analysis of the two unrelated fungal β-lactam producers Acremonium chrysogenum and Penicillium chrysogenum: Velvet-regulated genes are major targets during conventional strain improvement programs
per: Dominik Terfehr, et al.
Publicat: (2017-03-01)

Kinetic studies on the mechanism of the penicillin amidase-catalysed synthesis of ampicillin and benzylpenicillin /
per: 416857 Kasche, Volker, et al.

The significance of E. coli treatment in perinatal period
per: Ljubić Aleksandar D., et al.
Publicat: (2016-01-01)

Studies on Pyridine n-oxides
per: Knott, J, et al.
Publicat: (1995)

Old and New Beta-Lactamase Inhibitors: Molecular Structure, Mechanism of Action, and Clinical Use
per: Davide Carcione, et al.
Publicat: (2021-08-01)

Antimicrobial Desensitization: A Review of Published Protocols
per: Daniel B. Chastain, et al.
Publicat: (2019-08-01)

Drug-specific history, skin and in vitro tests can reduce the need for drug provocation tests in betalactam-hypersensitivity
per: Stefan Wöhrl, et al.
Publicat: (2021-04-01)

Total synthesis of neolignans.
per: Mak, Ching-Pong
Publicat: (2006)

Characterization of Extended-Spectrum Beta-lactamase from Escherichia coli and Klebsiella Species from North Eastern Nigeria
per: Yahaya Mohammed, et al.
Publicat: (2016-02-01)

Selection of Pseudomous melanogenum KY 3987 as a new ampicillin-producing bacteria/
per: Ryo Okachi

Pemodelan reaktor lapisan terpadat edaran-berulangan berkelompok untuk hidrolisis penicilin-g kepada 6-aminopenicillanic acid /
per: 463344 Lai, Kok Chean
Publicat: (1999)

Production of 6-Aminopenicillanic Acid with immobilized Escherichia coli Acylase /
per: Largerlof, E.

Conversion of Benzylpenicillin to 6-Aminopenicillin acid in a batch reactor and continuos feed stirred tank reactor using immobilized penicillin amidase /
per: 228923 Warburton, D.