LYSOSOMAL SPHINGOSINE STORAGE INDUCED BY MYCOLIC ACID MEDIATED INHIBITION OF THE NPC1 PROTEIN IS CENTRAL TO Mycobacterium tuberculosis INDUCED PATHOGENESIS

Geahča maid

• Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases.
  Dahkki: Lloyd-Evans, E, et al.
  Almmustuhtton: (2011)
• The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity
  Dahkki: Xue Lin, et al.
  Almmustuhtton: (2022-10-01)
• Site of inhibitory action of isoniazid in the synthesis of mycolic acids in Mycobacterium tuberculosis
  Dahkki: K. Takayama, et al.
  Almmustuhtton: (1975-07-01)
• Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.
  Dahkki: Lloyd-Evans, E, et al.
  Almmustuhtton: (2008)
• Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.
  Dahkki: Jeyakumar, M, et al.
  Almmustuhtton: (2002)