Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping

The yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase DDP1 is a Nudix enzyme with pyrophosphatase activity on diphosphoinositides, dinucleotides, and polyphosphates. These substrates bind to diverse protein targets and participate in signaling and metabolism, being essential for...

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Main Authors: Márquez-Moñino, MÁ, Ortega-García, R, Shipton, ML, Franco-Echevarría, E, Riley, AM, Sanz-Aparicio, J, Potter, BVL, González, B
Format: Journal article
Jezik:English
Izdano: American Association for the Advancement of Science 2021