Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: A multi-site omics study

Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: A multi-site omics study

Reproducibility in molecular and cellular studies is fundamental to scientific discovery. To establish the reproducibility of a well-defined long-term neuronal differentiation protocol, we repeated the cellular and molecular comparison of the same two iPSC lines across five distinct laboratories. De...

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Bibliographic Details
Main Authors: Volpato, V, Smith, J, Sandor, C, Ried, J, Baud, A, Handel, A, Newey, S, Wessely, F, Attar, M, Whiteley, E, Chintawar, S, Verheyen, A, Barta, T, Lako, M, Armstrong, L, Muschet, C, Artati, A, Cusulin, C, Christensen, K, Patsch, C, Sharma, E, Nicod, J, Brownjohn, P, Stubbs, V, Heywood, W, Gissen, P, De Filippis, R, Janssen, K, Reinhardt, P, Adamski, J, Royaux, I, Peeters, P, Terstappen, G, Graf, M, Livesey, F, Akerman, C, Mills, K, Bowden, R, Nicholson, G, Webber, C, Cader, M, Lakics, V
Format: Journal article
Language:English
Published: Elsevier 2018

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