Investigation of the signalling and function of NOD2

<p>NOD2 is an intracellular innate immune receptor expressed in dendritic cells and gastrointestinal epithelial cells. Polymorphisms in the NOD2 gene convey a strong predisposition to Crohn’s disease (CD), a form of inflammatory bowel disease. Understanding the function of NOD2, and in what wa...

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Bibliographic Details
Main Author: Brain, A
Other Authors: Simmons, A
Format: Thesis
Language:English
Published: 2013
Subjects: