Investigation of the signalling and function of NOD2
<p>NOD2 is an intracellular innate immune receptor expressed in dendritic cells and gastrointestinal epithelial cells. Polymorphisms in the NOD2 gene convey a strong predisposition to Crohn’s disease (CD), a form of inflammatory bowel disease. Understanding the function of NOD2, and in what wa...
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Format: | Thesis |
Language: | English |
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2013
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