Optimising CRISPR for targeting of primary haematopoietic stem cells
<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...
Päätekijä: | |
---|---|
Muut tekijät: | |
Aineistotyyppi: | Opinnäyte |
Kieli: | English |
Julkaistu: |
2021
|
Aiheet: |