Optimising CRISPR for targeting of primary haematopoietic stem cells

<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...

Täydet tiedot

Bibliografiset tiedot
Päätekijä: Field, L
Muut tekijät: Mead, A
Aineistotyyppi: Opinnäyte
Kieli:English
Julkaistu: 2021
Aiheet: