PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Inflammasomes are protein complexes in the innate immune system that regulate the production of pro-inflammatory cytokines and inflammatory cell death. Inflammasome activation and subsequent cell death often occur within minutes to an hour, so the pathway must be dynamically controlled to prevent ex...

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Bibliographic Details
Main Authors: McKee, CM, Fischer, FA, Bezbradica, JS, Coll, RC
Format: Journal article
Language:English
Published: Biochemical Society 2021