PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling
Inflammasomes are protein complexes in the innate immune system that regulate the production of pro-inflammatory cytokines and inflammatory cell death. Inflammasome activation and subsequent cell death often occur within minutes to an hour, so the pathway must be dynamically controlled to prevent ex...
Main Authors: | McKee, CM, Fischer, FA, Bezbradica, JS, Coll, RC |
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Format: | Journal article |
Language: | English |
Published: |
Biochemical Society
2021
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