Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis.

The pathogenesis of rheumatoid arthritis (RA) and osteoarthritis (OA) remains obscure, although angiogenesis appears to play an important role. We recently confirmed an overexpression of two angiogenic factors, namely vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell gr...

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Detalles Bibliográficos
Autores principales: Giatromanolaki, A, Sivridis, E, Maltezos, E, Athanassou, N, Papazoglou, D, Gatter, K, Harris, A, Koukourakis, M
Formato: Journal article
Lenguaje:English
Publicado: BioMed Central 2003