Plasmodium falciparum antigenic variation: relationships between in vivo selection, acquired antibody response, and disease severity.

BACKGROUND: Variant surface antigens (VSA) on Plasmodium falciparum-infected erythrocytes are potentially important targets of immunity to malaria. We previously identified a VSA phenotype--VSA with a high frequency of antibody recognition (VSA(FoRH))--that is associated with young host age and sev...

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Bibliographic Details
Main Authors: Bull, P, Pain, A, Ndungu, F, Kinyanjui, S, Roberts, D, Newbold, C, Marsh, K
Format: Journal article
Language:English
Published: 2005