CD4+ T cell fate decisions are stochastic, precede cell division, depend on GITR co-stimulation, and are associated with uropodium development
During an immune response, naïve CD4+ T cells proliferate and generate a range of effector, memory, and regulatory T cell subsets, but how these processes are coordinated remains unclear. A traditional model suggests that memory cells use mitochondrial respiration and are survivors from a pool of pr...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
Frontiers Media
2018
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