Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy
Programmed cell death ligand 1 (PD-L1) interacts with programmed cell death protein-1 (PD-1) as an immune checkpoint. Reactivating the immune response by inhibiting PD-L1 using therapeutic antibodies provides substantial clinical benefits in many, though not all, melanoma patients. However, transcri...
المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , , |
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التنسيق: | Journal article |
منشور في: |
Springer Nature
2018
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