Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Programmed cell death ligand 1 (PD-L1) interacts with programmed cell death protein-1 (PD-1) as an immune checkpoint. Reactivating the immune response by inhibiting PD-L1 using therapeutic antibodies provides substantial clinical benefits in many, though not all, melanoma patients. However, transcri...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Zhu, B, Tang, L, Chen, S, Yin, C, Peng, S, Li, X, Liu, T, Liu, W, Han, C, Stawski, L, Xu, Z, Zhou, G, Chen, X, Gao, X, Goding, C, Xu, N, Cui, R, Cao, P
Formatua:	Journal article
Argitaratua:	Springer Nature 2018

Antzeko izenburuak

Transcription regulation in melanocytes and melanoma
nork: Goding, C
Argitaratua: (2008)

The transcription network regulating melanocyte development and melanoma.
nork: Vance, K, et al.
Argitaratua: (2004)

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage.
nork: Goding, C
Argitaratua: (2000)

A targeted therapy for melanoma by graphene oxide composite with microRNA carrier
nork: Liu C, et al.
Argitaratua: (2018-09-01)

Recognition of the E-C4 element from the C4 complement gene promoter by the upstream stimulatory factor-1 transcription factor.
nork: Galibert, MD, et al.
Argitaratua: (1997)

Microphthalmic-associated transcription factor integrates melanocyte biology and melanoma progression.
nork: Goding, C, et al.
Argitaratua: (2006)

Targeting the lncRNA SAMMSON reveals metabolic vulnerability in melanoma
nork: Goding, C
Argitaratua: (2016)

SL4/PASPCR Aaron Lerner Lecture Signalling and transcription in melanoma stem-like cells
nork: Goding, C
Argitaratua: (2011)

Splicing activates transcription from weak promoters upstream of alternative exons
nork: Maritere Uriostegui-Arcos, et al.
Argitaratua: (2023-06-01)

The Brn-2 transcription factor links activated BRAF to melanoma proliferation.
nork: Goodall, J, et al.
Argitaratua: (2004)

Melanoma: markers and epigenetics
nork: Goding, C
Argitaratua: (2007)

Editorial: melanomas and Wnts.
nork: Goding, C
Argitaratua: (2005)

The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
nork: Jessen, C, et al.
Argitaratua: (2020)

Dendritic cells and melanoma therapy.
nork: Goding, C
Argitaratua: (2009)

T-box factors in melanocytes and melanoma
nork: Goding, C
Argitaratua: (2008)

Melanocyte development and malignant melanoma.
nork: Goding, C
Argitaratua: (2000)

Melanoma, making a difference
nork: Goding, C
Argitaratua: (2007)

Targeted Nanotherapeutics Using LACTB Gene Therapy Against Melanoma
nork: Liu J, et al.
Argitaratua: (2021-11-01)

Melanoma senescence: HDAC1 in focus.
nork: Goding, C
Argitaratua: (2007)

Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat
nork: Yanyan Liu, et al.
Argitaratua: (2024-12-01)

Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation
nork: Li, C, et al.
Argitaratua: (2024)

Targeting STAT3 Abrogates Tim-3 Upregulation of Adaptive Resistance to PD-1 Blockade on Regulatory T Cells of Melanoma
nork: Lili Huang, et al.
Argitaratua: (2021-04-01)

The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.
nork: Carreira, S, et al.
Argitaratua: (2000)

Back to black: Pigment cell and melanoma research
nork: Goding, C
Argitaratua: (2007)

Commentary. A picture of Mitf in melanoma immortality.
nork: Goding, C
Argitaratua: (2011)

Fishful thinking: the rise and fall of MITF in melanoma.
nork: Goding, C
Argitaratua: (2014)

Fishful thinking: the rise and fall of MITF in melanoma.
nork: Goding, C
Argitaratua: (2014)

Commentary. A picture of Mitf in melanoma immortality.
nork: Goding, C
Argitaratua: (2011)

Construction and Application of a PD-L1-Targeted Multimodal Diagnostic and Dual-Functional Theranostics Nanoprobe
nork: He C, et al.
Argitaratua: (2024-06-01)

ULF waves in Ganymede's upstream magnetosphere
nork: M. Volwerk, et al.
Argitaratua: (2013-01-01)

The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression.
nork: Eisen, T, et al.
Argitaratua: (1995)

CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth
nork: J. Yang, et al.
Argitaratua: (2023-06-01)

Palmitoylation-dependent activation of MC1R prevents melanomagenesis
nork: Chen, S, et al.
Argitaratua: (2017)

A Multifunctional Low-Temperature Photothermal Nanomedicine for Melanoma Treatment via the Oxidative Stress Pathway Therapy
nork: Zhang D, et al.
Argitaratua: (2024-11-01)

Melanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway
nork: Wang C, et al.
Argitaratua: (2020-12-01)

Identification and validation of organ-preferential genes and analysis of corresponding upstream tissue-specific promoters in wheat
nork: P.P. Su, et al.
Argitaratua: (2019-01-01)

Targeting Hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells
nork: Goding, C, et al.
Argitaratua: (2016)

Macrophage cytoplasmic transfer in melanoma invasion
nork: Louphrasitthiphol, P, et al.
Argitaratua: (2017)

CD44-Targeting Oxygen Self-Sufficient Nanoparticles for Enhanced Photodynamic Therapy Against Malignant Melanoma
nork: Hou X, et al.
Argitaratua: (2020-12-01)

Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells.
nork: Goodall, J, et al.
Argitaratua: (2008)