Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Programmed cell death ligand 1 (PD-L1) interacts with programmed cell death protein-1 (PD-1) as an immune checkpoint. Reactivating the immune response by inhibiting PD-L1 using therapeutic antibodies provides substantial clinical benefits in many, though not all, melanoma patients. However, transcri...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Zhu, B, Tang, L, Chen, S, Yin, C, Peng, S, Li, X, Liu, T, Liu, W, Han, C, Stawski, L, Xu, Z, Zhou, G, Chen, X, Gao, X, Goding, C, Xu, N, Cui, R, Cao, P
Формат:	Journal article
Хэвлэсэн:	Springer Nature 2018

Ижил төстэй зүйлс

Transcription regulation in melanocytes and melanoma
-н: Goding, C
Хэвлэсэн: (2008)

The transcription network regulating melanocyte development and melanoma.
-н: Vance, K, зэрэг
Хэвлэсэн: (2004)

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage.
-н: Goding, C
Хэвлэсэн: (2000)

A targeted therapy for melanoma by graphene oxide composite with microRNA carrier
-н: Liu C, зэрэг
Хэвлэсэн: (2018-09-01)

Recognition of the E-C4 element from the C4 complement gene promoter by the upstream stimulatory factor-1 transcription factor.
-н: Galibert, MD, зэрэг
Хэвлэсэн: (1997)

Microphthalmic-associated transcription factor integrates melanocyte biology and melanoma progression.
-н: Goding, C, зэрэг
Хэвлэсэн: (2006)

Targeting the lncRNA SAMMSON reveals metabolic vulnerability in melanoma
-н: Goding, C
Хэвлэсэн: (2016)

SL4/PASPCR Aaron Lerner Lecture Signalling and transcription in melanoma stem-like cells
-н: Goding, C
Хэвлэсэн: (2011)

Splicing activates transcription from weak promoters upstream of alternative exons
-н: Maritere Uriostegui-Arcos, зэрэг
Хэвлэсэн: (2023-06-01)

The Brn-2 transcription factor links activated BRAF to melanoma proliferation.
-н: Goodall, J, зэрэг
Хэвлэсэн: (2004)

Melanoma: markers and epigenetics
-н: Goding, C
Хэвлэсэн: (2007)

Editorial: melanomas and Wnts.
-н: Goding, C
Хэвлэсэн: (2005)

The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
-н: Jessen, C, зэрэг
Хэвлэсэн: (2020)

Dendritic cells and melanoma therapy.
-н: Goding, C
Хэвлэсэн: (2009)

T-box factors in melanocytes and melanoma
-н: Goding, C
Хэвлэсэн: (2008)

Melanocyte development and malignant melanoma.
-н: Goding, C
Хэвлэсэн: (2000)

Melanoma, making a difference
-н: Goding, C
Хэвлэсэн: (2007)

Targeted Nanotherapeutics Using LACTB Gene Therapy Against Melanoma
-н: Liu J, зэрэг
Хэвлэсэн: (2021-11-01)

Melanoma senescence: HDAC1 in focus.
-н: Goding, C
Хэвлэсэн: (2007)

Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat
-н: Yanyan Liu, зэрэг
Хэвлэсэн: (2024-12-01)

Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation
-н: Li, C, зэрэг
Хэвлэсэн: (2024)

Targeting STAT3 Abrogates Tim-3 Upregulation of Adaptive Resistance to PD-1 Blockade on Regulatory T Cells of Melanoma
-н: Lili Huang, зэрэг
Хэвлэсэн: (2021-04-01)

The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.
-н: Carreira, S, зэрэг
Хэвлэсэн: (2000)

Back to black: Pigment cell and melanoma research
-н: Goding, C
Хэвлэсэн: (2007)

Commentary. A picture of Mitf in melanoma immortality.
-н: Goding, C
Хэвлэсэн: (2011)

Fishful thinking: the rise and fall of MITF in melanoma.
-н: Goding, C
Хэвлэсэн: (2014)

Fishful thinking: the rise and fall of MITF in melanoma.
-н: Goding, C
Хэвлэсэн: (2014)

Commentary. A picture of Mitf in melanoma immortality.
-н: Goding, C
Хэвлэсэн: (2011)

Construction and Application of a PD-L1-Targeted Multimodal Diagnostic and Dual-Functional Theranostics Nanoprobe
-н: He C, зэрэг
Хэвлэсэн: (2024-06-01)

ULF waves in Ganymede's upstream magnetosphere
-н: M. Volwerk, зэрэг
Хэвлэсэн: (2013-01-01)

The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression.
-н: Eisen, T, зэрэг
Хэвлэсэн: (1995)

CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth
-н: J. Yang, зэрэг
Хэвлэсэн: (2023-06-01)

Palmitoylation-dependent activation of MC1R prevents melanomagenesis
-н: Chen, S, зэрэг
Хэвлэсэн: (2017)

A Multifunctional Low-Temperature Photothermal Nanomedicine for Melanoma Treatment via the Oxidative Stress Pathway Therapy
-н: Zhang D, зэрэг
Хэвлэсэн: (2024-11-01)

Melanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway
-н: Wang C, зэрэг
Хэвлэсэн: (2020-12-01)

Identification and validation of organ-preferential genes and analysis of corresponding upstream tissue-specific promoters in wheat
-н: P.P. Su, зэрэг
Хэвлэсэн: (2019-01-01)

Targeting Hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells
-н: Goding, C, зэрэг
Хэвлэсэн: (2016)

Macrophage cytoplasmic transfer in melanoma invasion
-н: Louphrasitthiphol, P, зэрэг
Хэвлэсэн: (2017)

CD44-Targeting Oxygen Self-Sufficient Nanoparticles for Enhanced Photodynamic Therapy Against Malignant Melanoma
-н: Hou X, зэрэг
Хэвлэсэн: (2020-12-01)

Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells.
-н: Goodall, J, зэрэг
Хэвлэсэн: (2008)