Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Programmed cell death ligand 1 (PD-L1) interacts with programmed cell death protein-1 (PD-1) as an immune checkpoint. Reactivating the immune response by inhibiting PD-L1 using therapeutic antibodies provides substantial clinical benefits in many, though not all, melanoma patients. However, transcri...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Zhu, B, Tang, L, Chen, S, Yin, C, Peng, S, Li, X, Liu, T, Liu, W, Han, C, Stawski, L, Xu, Z, Zhou, G, Chen, X, Gao, X, Goding, C, Xu, N, Cui, R, Cao, P
स्वरूप:	Journal article
प्रकाशित:	Springer Nature 2018

समान संसाधन

Transcription regulation in melanocytes and melanoma
द्वारा: Goding, C
प्रकाशित: (2008)

The transcription network regulating melanocyte development and melanoma.
द्वारा: Vance, K, और अन्य
प्रकाशित: (2004)

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage.
द्वारा: Goding, C
प्रकाशित: (2000)

A targeted therapy for melanoma by graphene oxide composite with microRNA carrier
द्वारा: Liu C, और अन्य
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Recognition of the E-C4 element from the C4 complement gene promoter by the upstream stimulatory factor-1 transcription factor.
द्वारा: Galibert, MD, और अन्य
प्रकाशित: (1997)

Microphthalmic-associated transcription factor integrates melanocyte biology and melanoma progression.
द्वारा: Goding, C, और अन्य
प्रकाशित: (2006)

Targeting the lncRNA SAMMSON reveals metabolic vulnerability in melanoma
द्वारा: Goding, C
प्रकाशित: (2016)

SL4/PASPCR Aaron Lerner Lecture Signalling and transcription in melanoma stem-like cells
द्वारा: Goding, C
प्रकाशित: (2011)

Splicing activates transcription from weak promoters upstream of alternative exons
द्वारा: Maritere Uriostegui-Arcos, और अन्य
प्रकाशित: (2023-06-01)

The Brn-2 transcription factor links activated BRAF to melanoma proliferation.
द्वारा: Goodall, J, और अन्य
प्रकाशित: (2004)

Melanoma: markers and epigenetics
द्वारा: Goding, C
प्रकाशित: (2007)

Editorial: melanomas and Wnts.
द्वारा: Goding, C
प्रकाशित: (2005)

The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
द्वारा: Jessen, C, और अन्य
प्रकाशित: (2020)

Dendritic cells and melanoma therapy.
द्वारा: Goding, C
प्रकाशित: (2009)

T-box factors in melanocytes and melanoma
द्वारा: Goding, C
प्रकाशित: (2008)

Melanocyte development and malignant melanoma.
द्वारा: Goding, C
प्रकाशित: (2000)

Melanoma, making a difference
द्वारा: Goding, C
प्रकाशित: (2007)

Targeted Nanotherapeutics Using LACTB Gene Therapy Against Melanoma
द्वारा: Liu J, और अन्य
प्रकाशित: (2021-11-01)

Melanoma senescence: HDAC1 in focus.
द्वारा: Goding, C
प्रकाशित: (2007)

Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat
द्वारा: Yanyan Liu, और अन्य
प्रकाशित: (2024-12-01)

Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation
द्वारा: Li, C, और अन्य
प्रकाशित: (2024)

Targeting STAT3 Abrogates Tim-3 Upregulation of Adaptive Resistance to PD-1 Blockade on Regulatory T Cells of Melanoma
द्वारा: Lili Huang, और अन्य
प्रकाशित: (2021-04-01)

The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.
द्वारा: Carreira, S, और अन्य
प्रकाशित: (2000)

Back to black: Pigment cell and melanoma research
द्वारा: Goding, C
प्रकाशित: (2007)

Commentary. A picture of Mitf in melanoma immortality.
द्वारा: Goding, C
प्रकाशित: (2011)

Fishful thinking: the rise and fall of MITF in melanoma.
द्वारा: Goding, C
प्रकाशित: (2014)

Fishful thinking: the rise and fall of MITF in melanoma.
द्वारा: Goding, C
प्रकाशित: (2014)

Commentary. A picture of Mitf in melanoma immortality.
द्वारा: Goding, C
प्रकाशित: (2011)

Construction and Application of a PD-L1-Targeted Multimodal Diagnostic and Dual-Functional Theranostics Nanoprobe
द्वारा: He C, और अन्य
प्रकाशित: (2024-06-01)

ULF waves in Ganymede's upstream magnetosphere
द्वारा: M. Volwerk, और अन्य
प्रकाशित: (2013-01-01)

The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression.
द्वारा: Eisen, T, और अन्य
प्रकाशित: (1995)

CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth
द्वारा: J. Yang, और अन्य
प्रकाशित: (2023-06-01)

Palmitoylation-dependent activation of MC1R prevents melanomagenesis
द्वारा: Chen, S, और अन्य
प्रकाशित: (2017)

A Multifunctional Low-Temperature Photothermal Nanomedicine for Melanoma Treatment via the Oxidative Stress Pathway Therapy
द्वारा: Zhang D, और अन्य
प्रकाशित: (2024-11-01)

Melanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway
द्वारा: Wang C, और अन्य
प्रकाशित: (2020-12-01)

Identification and validation of organ-preferential genes and analysis of corresponding upstream tissue-specific promoters in wheat
द्वारा: P.P. Su, और अन्य
प्रकाशित: (2019-01-01)

Targeting Hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells
द्वारा: Goding, C, और अन्य
प्रकाशित: (2016)

Macrophage cytoplasmic transfer in melanoma invasion
द्वारा: Louphrasitthiphol, P, और अन्य
प्रकाशित: (2017)

CD44-Targeting Oxygen Self-Sufficient Nanoparticles for Enhanced Photodynamic Therapy Against Malignant Melanoma
द्वारा: Hou X, और अन्य
प्रकाशित: (2020-12-01)

Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells.
द्वारा: Goodall, J, और अन्य
प्रकाशित: (2008)