Mechanisms of the glycaemic effects of sulfonylureas.

Sulfonylureas are widely used to treat non-insulin dependent diabetes mellitus. These drugs exert their hypoglycaemic effects by stimulating insulin secretion from the pancreatic beta-cell. Their primary mechanism of action is to close ATP-sensitive K-channels in the beta-cell plasma membrane, and s...

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Detaylı Bibliyografya
Yazar: Ashcroft, F
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 1996