Mechanisms of the glycaemic effects of sulfonylureas.
Sulfonylureas are widely used to treat non-insulin dependent diabetes mellitus. These drugs exert their hypoglycaemic effects by stimulating insulin secretion from the pancreatic beta-cell. Their primary mechanism of action is to close ATP-sensitive K-channels in the beta-cell plasma membrane, and s...
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| Format: | Journal article |
| Język: | English |
| Wydane: |
1996
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