Mechanisms of the glycaemic effects of sulfonylureas.
Sulfonylureas are widely used to treat non-insulin dependent diabetes mellitus. These drugs exert their hypoglycaemic effects by stimulating insulin secretion from the pancreatic beta-cell. Their primary mechanism of action is to close ATP-sensitive K-channels in the beta-cell plasma membrane, and s...
Autor principal: | |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
1996
|