Crystal structure of a human GABAA receptor

Type-A γ-aminobutyric acid receptors (GABAA Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABAA R signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy. Here we present the first three-dimensional st...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Miller, P, Aricescu, A
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Nature Publishing Group 2014