Identification of a gene (lpt-3) required for the addition of phosphoethanolamine to the lipopolysaccharide inner core of Neisseria meningitidis and its role in mediating susceptibility to bactericidal killing and opsonophagocytosis.

We have identified a gene, lpt-3, that is required for the addition of phosphoethanolamine to the 3-position (PEtn-3) on the beta-chain heptose (HepII) of the inner core lipopolysaccharide (LPS) of Neisseria meningitidis (Nm). The presence of this PEtn-3 substituent is characteristic of the LPS of a...

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প্রধান লেখক: Mackinnon, F, Cox, A, Plested, J, Tang, C, Makepeace, K, Coull, P, Wright, J, Chalmers, R, Hood, D, Richards, J, Moxon, E
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2002