Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer

Frizzled receptors mediate Wnt ligand signalling, which is crucially involved in regulating tissue development and differentiation, and is often deregulated in cancer. In this study, we found that the gene encoding the Wnt receptor frizzled 6 (FZD6) is frequently amplified in breast cancer, with an...

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Main Authors: Corda, G, Sala, G, Lattanzio, R, Iezzi, M, Sallese, M, Fragassi, G, Lamolinara, A, Mirza, H, Barcaroli, D, Ermler, S, Silva, E, Yasaei, H, Newbold, R, Vagnarelli, P, Mottolese, M, Natali, P, Perracchio, L, Quist, J, Grigoriadis, A, Marra, P, Tutt, A, Piantelli, M, Iacobelli, S, De Laurenzi, V, Sala, A
Format: Journal article
Language:English
Published: John Wiley & Sons Ltd 2016