Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R

The phosphatidylserine receptor TIM4, encoded by TIMD4, mediates the phagocytic uptake of apoptotic cells. We applied anti-chicken TIM4 mAbs in combination with CSF1R reporter transgenes to dissect the function of TIM4 in the chick (Gallus gallus). During development in ovo, TIM4 was present on the...

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Bibliographic Details
Main Authors: Hu, T, Wu, Z, Bush, S, Freem, L, Vervelde, L, Summers, K, Hume, D, Balic, A, Kaiser, P
Format: Journal article
Language:English
Published: American Society of Immunologists 2019