ANRIL, THE NON CODING RNA PRESENT IN THE CHROMOSOME 9 CAD ASSOCIATED LOCUS, HAS MULTIPLE SPLICE VARIANTS AND A POTENTIAL REGULATORY ROLE IN CDKN2B EXPRESSION

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• Gene expression analysis demonstrates presence of a non-coding RNA (ANRIL) in human islets and FACs sorted beta cells which has a potential regulatory role on CDKN2B expression
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• Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
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• Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p.
  著者:: Broadbent, H, 等
  出版事項: (2008)
• Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
  著者:: Broadbent, H, 等
  出版事項: (2008)