Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial

BACKGROUND:There is an urgent need for an effective tuberculosis (TB) vaccine. Heterologous prime-boost regimens induce potent cellular immunity. MVA85A is a candidate TB vaccine. This phase I clinical trial was designed to evaluate whether alternating aerosol and intradermal vaccination routes woul...

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Bibliographic Details
Main Authors: Manjaly Thomas, Z, Satti, I, Marshall, J, Harris, S, Lopez Ramon, R, Hamidi, A, Minhinnick, A, Riste, M, Stockdale, L, Lawrie, A, Vermaak, S, Wilkie, M, Bettinson, H, McShane, H
Format: Journal article
Language:English
Published: Public Library of Science 2019