Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-Tubulin Ring Complex to the mitotic spindle
The hetero-octameric protein complex, Augmin, recruits γ-Tubulin Ring Complex (γ-TuRC) to pre-existing microtubules (MTs) to generate branched MTs during mitosis, facilitating robust spindle assembly. However, despite a recent partial reconstitution of the human Augmin complex in vitro, the molecula...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Published: |
Company of Biologists
2017
|