Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-Tubulin Ring Complex to the mitotic spindle
The hetero-octameric protein complex, Augmin, recruits γ-Tubulin Ring Complex (γ-TuRC) to pre-existing microtubules (MTs) to generate branched MTs during mitosis, facilitating robust spindle assembly. However, despite a recent partial reconstitution of the human Augmin complex in vitro, the molecula...
Main Authors: | Chen, J, Chen, Z, Rogala, K, Metz, J, Deane, C, Rappsiber, J, Wakefield, J |
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Format: | Journal article |
Published: |
Company of Biologists
2017
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