Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice.

We have localized a set of T cell-specific DNAase I hypersensitive sites in the 3'-flanking region of the human CD2 gene. A 5.5 kb BamHI-XbaI fragment containing these DNAase I hypersensitive sites conferred efficient, copy number-dependent, T cell-specific expression of a linked human CD2 mini...

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Detalhes bibliográficos
Main Authors: Greaves, D, Wilson, F, Lang, G, Kioussis, D
Formato: Journal article
Idioma:English
Publicado em: 1989