Physiological and pathological properties of alpha-synuclein.
alpha-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind to lipid membranes and acquire a partial alpha-helical conformation. Under certain pathogenic conditions, alpha-synuclein aggregates to form oligomers and insoluble fibrils with increased ss-sheet config...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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