Pharmacological characterization of the putative cADP-ribose receptor.
cADP-ribose (cADPR), a naturally occurring metabolite of NAD(+), has been shown to be an important regulator of intracellular Ca(2+) release. Considerable evidence suggests that cADPR is the endogenous modulator of the ryanodine receptor (RyR), which mediates Ca(2+)-induced Ca(2+) release (CICR). In...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2001
|