Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation.

The lipid carrier specificity of the protein N-glycosylation enzyme C. jejuni PglB was tested using a logical, synthetic array of natural and unnatural C10, C20, C30, and C40 polyisoprenol sugar pyrophosphates, including those bearing repeating cis-prenyl units. Unusual, short, synthetically accessi...

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Bibliographic Details
Main Authors: Liu, F, Vijayakrishnan, B, Faridmoayer, A, Taylor, T, Parsons, T, Bernardes, G, Kowarik, M, Davis, B
Format: Journal article
Language:English
Published: 2014