From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.

The regulation of blood red cell production by the hormone erythropoietin (Epo) provides a paradigm for control of gene expression by oxygen. Analysis of this pathway has revealed a widespread system of gene regulation based on a transcriptional complex termed hypoxia-inducible factor (HIF). Hydroxy...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Ratcliffe, P
التنسيق: Conference item
منشور في: 2002