From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.

The regulation of blood red cell production by the hormone erythropoietin (Epo) provides a paradigm for control of gene expression by oxygen. Analysis of this pathway has revealed a widespread system of gene regulation based on a transcriptional complex termed hypoxia-inducible factor (HIF). Hydroxy...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч:	Ratcliffe, P
Формат:	Conference item
Хэвлэсэн:	2002

Ижил төстэй зүйлс

Signalling hypoxia by HIF hydroxylases.
-н: Schofield, C, зэрэг
Хэвлэсэн: (2005)

Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics
-н: Ratcliffe, P, зэрэг
Хэвлэсэн: (2017)

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
-н: Webb, J, зэрэг
Хэвлэсэн: (2009)

Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
-н: Ehrismann, D, зэрэг
Хэвлэсэн: (2007)

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
-н: Tian, Y, зэрэг
Хэвлэсэн: (2011)

The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha.
-н: Willam, C, зэрэг
Хэвлэсэн: (2004)

Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
-н: Hewitson, K, зэрэг
Хэвлэсэн: (2007)

Evaluation of aspirin metabolites as inhibitors of hypoxia-inducible factor hydroxylases.
-н: Lienard, B, зэрэг
Хэвлэсэн: (2008)

Biochemistry of the hypoxia-inducible factor hydroxylases
-н: Fiorini, G, зэрэг
Хэвлэсэн: (2024)

Kinetic investigations of the oxygen entry pathway of the hypoxia-inducible factor (HIF) prolyl hydroxylase 2
-н: Kearney, L
Хэвлэсэн: (2015)

Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer.
-н: Ratcliffe, P
Хэвлэсэн: (2013)

FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase.
-н: Ingo Flamme, зэрэг
Хэвлэсэн: (2017-01-01)

Inhibition of hypoxia inducible factor (HIF) hydroxylases
-н: Conejo-Garcia, A, зэрэг
Хэвлэсэн: (2005)

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
-н: Chowdhury, R, зэрэг
Хэвлэсэн: (2009)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
-н: Flashman, E, зэрэг
Хэвлэсэн: (2010)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
-н: Flashman, E, зэрэг
Хэвлэсэн: (2010)

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice.
-н: Ratcliffe, P, зэрэг
Хэвлэсэн: (2016)

Mammalian oxygen sensing and hypoxia inducible factor-1
-н: Wood, S, зэрэг
Хэвлэсэн: (1997)

Inhibition of the oxygen-sensing asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor: a potential hypoxia response modulating strategy
-н: Wu, Y, зэрэг
Хэвлэсэн: (2021)

Oxygen sensing and hypoxia-induced responses.
-н: Coleman, M, зэрэг
Хэвлэсэн: (2007)

Induction of hypoxia-inducible factor-1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: evidence against a regulatory role for Src kinase.
-н: Gleadle, J, зэрэг
Хэвлэсэн: (1997)

New horizons in hypoxia signaling pathways
-н: Pugh, C, зэрэг
Хэвлэсэн: (2017)

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing.
-н: Gleadle, J, зэрэг
Хэвлэсэн: (1995)

Inhibition studies on hypoxia-inducible factor (HIF) hydroxylases
-н: Chan, M
Хэвлэсэн: (2014)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
-н: Stolze, I, зэрэг
Хэвлэсэн: (2004)

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
-н: McDonough, M, зэрэг
Хэвлэсэн: (2006)

Hypoxia-inducible erythropoietin expression: details matter
-н: Thomas Kietzmann
Хэвлэсэн: (2020-12-01)

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
-н: Chowdhury, R, зэрэг
Хэвлэсэн: (2013)

Studies on the inhibition of human hypoxia inducible factor (HIF) hydroxylases
-н: Yeoh, KK
Хэвлэсэн: (2012)

Hypoxia inducible factor prolyl hydroxylases in inflammatory bowel disease
-н: Jie Lun, зэрэг
Хэвлэсэн: (2023-05-01)

New horizons in hypoxia signaling pathways in health and disease
-н: Ratcliffe, P
Хэвлэсэн: (2018)

Hypoxia Signalling and Disease
-н: Ratcliffe, P
Хэвлэсэн: (2010)

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.
-н: Lancaster, D, зэрэг
Хэвлэсэн: (2004)

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
-н: Moritz J. Strowitzki, зэрэг
Хэвлэсэн: (2019-04-01)

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
-н: Loenarz, C, зэрэг
Хэвлэсэн: (2010)

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens.
-н: Loenarz, C, зэрэг
Хэвлэсэн: (2011)

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
-н: Loenarz, C, зэрэг
Хэвлэсэн: (2011)

Distribution of erythropoietin producing cells in rat kidneys during hypoxic hypoxia.
-н: Eckardt, K, зэрэг
Хэвлэсэн: (1993)

Bibliometric analysis of hypoxia inducible factor prolyl hydroxylase inhibitor in anemia
-н: Li Zheng, зэрэг
Хэвлэсэн: (2022-09-01)

Hypoxia-Inducible Factor-Proline Hydroxylase Inhibitor in the Treatment of Renal Anemia
-н: Xiaofan Hu, зэрэг
Хэвлэсэн: (2020-12-01)