From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
The regulation of blood red cell production by the hormone erythropoietin (Epo) provides a paradigm for control of gene expression by oxygen. Analysis of this pathway has revealed a widespread system of gene regulation based on a transcriptional complex termed hypoxia-inducible factor (HIF). Hydroxy...
Prif Awdur: | Ratcliffe, P |
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Fformat: | Conference item |
Cyhoeddwyd: |
2002
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Eitemau Tebyg
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Signalling hypoxia by HIF hydroxylases.
gan: Schofield, C, et al.
Cyhoeddwyd: (2005) -
Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics
gan: Ratcliffe, P, et al.
Cyhoeddwyd: (2017) -
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
gan: Webb, J, et al.
Cyhoeddwyd: (2009) -
Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
gan: Ehrismann, D, et al.
Cyhoeddwyd: (2007) -
Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
gan: Tian, Y, et al.
Cyhoeddwyd: (2011)