From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
The regulation of blood red cell production by the hormone erythropoietin (Epo) provides a paradigm for control of gene expression by oxygen. Analysis of this pathway has revealed a widespread system of gene regulation based on a transcriptional complex termed hypoxia-inducible factor (HIF). Hydroxy...
मुख्य लेखक: | Ratcliffe, P |
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स्वरूप: | Conference item |
प्रकाशित: |
2002
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समान संसाधन
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Signalling hypoxia by HIF hydroxylases.
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Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics
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Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
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Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
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