From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
The regulation of blood red cell production by the hormone erythropoietin (Epo) provides a paradigm for control of gene expression by oxygen. Analysis of this pathway has revealed a widespread system of gene regulation based on a transcriptional complex termed hypoxia-inducible factor (HIF). Hydroxy...
| Autor Principal: | |
|---|---|
| Formato: | Conference item |
| Publicado: |
2002
|