Analysis of in vitro follicle development during the onset of premature ovarian insufficiency in a mouse model
Premature ovarian insufficiency (POI) occurs in 1% of women under 40 years and is predominantly idiopathic. A transgenic mouse model of follicular POI, the Double Mutant (DM), are fertile at 6-weeks of age, become infertile by 9-weeks and exhibit POI by 3-months. DM female mice generate oocytes lack...
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Format: | Journal article |
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CSIRO Publishing
2016
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