Regulation of insulin granule exocytosis

Insulin is stored in secretory granules within the pancreatic beta cell. The release of insulin requires the fusion of the secretory granule with the plasma membrane and the discharge of the granule contents into the extracellular space. Insulin secretion follows a characteristic biphasic time cours...

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Bibliographic Details
Main Authors: Renström, E, Rorsman, P
Format: Book section
Published: Springer Japan 2008